Dementia: Alzheimer's Disease

0
14KB

Alzheimer's disease accounts for 60–70% of cases of dementia worldwide. The most common symptoms of Alzheimer's disease are short-term memory loss and word-finding difficulties. Trouble with visuospatial functioning (getting lost often), reasoning, judgment and insight fail. Insight refers to whether or not the person realizes they have memory problems.

The part of the brain most affected by Alzheimer's is the hippocampus. Other parts that show atrophy (shrinking) include the temporal and parietal lobes. Although this pattern of brain shrinkage suggests Alzheimer's, it is variable and a brain scan is insufficient for a diagnosis. The relationship between general anesthesia and Alzheimer's in elderly people is unclear.

Little is known about the events that occur during and that actually cause Alzheimer's disease. This is due to the fact that brain tissue from patients with the disease can only be studied after the person's death. However, it is known that one of the first aspects of the disease is a dysfunction in the gene that produces amyloid. Extracellular senile plaques (SPs), consisting of beta-amyloid (Aβ) peptides, and intracellular neurofibrillary tangles (NFTs) that are formed by hyperphosphorylated tau proteins, are two well-established pathological hallmarks of AD. Amyloid causes inflammation around the senile plaques of the brain, and too much build up of this inflammation leads to changes in the brain that cannot be controlled, leading to the symptoms of Alzheimer's.

Suche
Kategorien
Mehr lesen
Horror
A Quiet Place Part II. (2021)
Following the events at home, the Abbott family now face the terrors of the outside world. Forced...
Von Leonard Pokrovski 2022-09-22 14:48:07 0 41KB
Home Automation
Home Automation: Revolutionizing the Way We Live
In recent years, the concept of home automation has moved from a futuristic dream to a...
Von Dacey Rankins 2024-11-08 17:09:38 0 10KB
Volleyball
Volleyball
Volleyball (English volleyball from volley - "blow from the flight" and ball - "ball") is a...
Von FWhoop Xelqua 2023-02-24 17:26:22 0 14KB
Business
What Questions Do Investors Commonly Ask Startup CEOs?
For startup CEOs, investor meetings are critical milestones. These conversations go beyond just...
Von Dacey Rankins 2025-05-06 12:50:21 0 4KB
Business
What Is Scope Creep, and How Can It Be Managed?
Scope creep is a common challenge in project management, referring to the uncontrolled expansion...
Von Dacey Rankins 2025-05-15 14:36:15 0 3KB
image/svg+xml


BigMoney.VIP Powered by Hosting Pokrov